![]() ![]() Increase in automated blood cell analyzers' availability has provided indices that were not previously calculated in manually performed CBCs, such as Red Blood Cell Distribution Width (RDW), which has led to new approaches in anemic patients (Balarin et al 2001, Žvorc et al 2010, Temizel et al 2011, Souza et al 2012). Palabras clave: plaquetas, anisocitosis, contador automatizado de hematología, Amplitud de Distribución Plaquetaria.Ī complete blood count (CBC) is an important tool for assessing animal's clinical status since it provides quantitative and qualitative information on all blood cells (Rizzi et al 2010). El L-PCR también es importante en perros trombocitopénicos, principalmente cuando son asociados a la presencia de plaquetas grandes en el extendido de sangre. ![]() Se concluyó que el PDW y el P-LCR aumentan en perros trombocitopénicos y son más sensibles que el MPV. Los resultados sugieren un aumento de la trombopoyesis y de la liberación de plaquetas con tamaños diferentes. No hubo diferencias significativas en ninguno de los índices entre los grupos trombocitopénicos. Los promedios de los índices de PDW y P-LCR en los trombocitopénicos fueron significativamente mayores que aquellos de animales con recuentos plaquetarios normales. Se dividieron los perros trombocitopénicos entre los que presentaban menos que 150.000 plaquetas/μL de sangre (19/42,2%) y los que tenían más que 150.000 plaquetas/μL de sangre (26/57,8%). Los perros fueron divididos entre los trombocitopénicos (45) y aquellos con recuentos plaquetarios normales (306). Fueron analizados los resultados de 351 hemogramas procesados en un contador automatizado de hematología veterinaria Sysmex ® pocH-100iV Diff. El objetivo del estudio consistió en evaluar el patrón de los índices plaquetarios (MPV, PDW y P-LCR ) en perros trombocitopénicos y perros con valores plaquetarios normales. Utilizando analizadores automatizados, los índices plaquetarios como el Volumen Plaquetario Medio (MPV), la Amplitud de Distribución Plaquetaria (PDW) y el Porcentaje de Plaquetas Grandes (P-LCR) han sido exámenes rutineros, permitiendo comparaciones de datos y verificaciones de errores y, consecuentemente, un mayor control de calidad. Es conocido que la trombocitopenia es el trastorno hemostático más común de los perros y una potencial amenaza de vida. Key words: platelets, anisocytosis, blood cell analyzer, platelet distribution width. P-LCR is also important in thrombocytopenic dogs, especially when associated to the presence of large platelets in blood smears. It was concluded that both PDW and P-LCR increase in dogs with thrombocytopenia and they are more sensitive than MPV. Results suggested increased thrombopoiesis and release of different sized platelets. ![]() Macroplatelets were present in the blood smears of thrombocytopenic dogs. There was no significant difference in any of the indices in either group of thrombocytopenic dogs. Mean values of PDW and P-LCR indices in thrombocytopenic animals were significantly higher than the mean values of animals with normal platelet counts. Thrombocytopenic dogs were subdivided in dogs with less than 150,000 platelets/μL of blood (19/42,2%) and dogs with over 150,000 platelets /μL of blood (26/ 57,8%). Two groups of dogs were established, those with thrombocytopenia (45) and those with normal platelet counts (306). The results of 351 CBCs processed in an automated veterinary haematology counter Sysmex ® pocH-100iV Diff were analysed. The aim of this study was to evaluate the pattern of platelet indices (MPV, PDW and P-LCR) in dogs with thrombocytopenia and with normal platelet values. With the use of automated analysers, platelet indices such as Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), and Platelet Large Cell Ratio (P-LCR), became routinely available, allowing data comparison and error checks which results in a more effective quality control. * Corresponding author: AM Souza Rua Vital Brazil Filho 64, Vital Brazil, Niterói, RJ 21230-360, Brazil It is well known that thrombocytopenia is the most commonly acquired haemostatic disorder in dogs and can be potentially life-threatening. Índices plaquetarios en perros con trombocitopenia y perros con recuentos de plaquetas normalesĪM Souza a *, JJ Pereira a, SDE Campos a, RA Torres-Filho b, MS Xavier a, DTL Bacellar c, NRP Almosny aĪ Departamento de Patologia e Clínica Veterinária, Faculdade de Veterinária, Universidade Federal Fluminense, Niteroi, Brazil.ī Departamento de Zootecnia, Faculdade de Veterinária, Universidade Federal Fluminense, Niterói, Brazil.Ĭ Instituto Nacional de Controle de Qualidade em Saúde, FIOCRUZ, Rio de Janeiro, Brasil. Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts ![]()
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